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Article

Mutations in the RNA polymerase II transcription machinery suppress the hyperrecombination mutant hpr1 delta of Saccharomyces cerevisiae.

Genetics - 1 Mar 1996

Fan H Y, Cheng K K, Klein H L

Abstract excerpt

The soh1, soh2 and soh4 mutants were isolated as suppressors of the temperature-dependent growth of the hyperrecombination mutant hpr1 of Saccharomyces cerevisiae. Cloning and sequence analysis of these suppressor genes has unexpectedly shown them to code for components of the RNA polymerase II transcription complex. SOH2 is identical to RPB2, which encodes the second largest subunit of RNA polymerase II, and...

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Identifiers

PMID: 8849885
DOI: 10.1093/genetics/142.3.749
PMCID: PMC1207016

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