Article
Characterization of mutations that suppress the temperature-sensitive growth of the hpr1 delta mutant of Saccharomyces cerevisiae.
Genetics - 1 Aug 1994
Fan H Y, Klein H L
Abstract excerpt
The hpr1 delta 3 mutant of Saccharomyces cerevisiae is temperature-sensitive for growth at 37 degrees and has a 1000-fold increase in deletion of tandem direct repeats. The hyperrecombination phenotype, measured by deletion of a leu2 direct repeat, is partially dependent on the RAD1 and RAD52 gen...
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- DNA Mutational Analysis
- DNA, Fungal
- Epistasis, Genetic
- Fungal Proteins
- Genes, Fungal
- Genes, Lethal
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Phenotype
- Recombination, Genetic
- Repetitive Sequences, Nucleic Acid
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Deletion