Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Requirement of S. pombe exonuclease II, a homologue of S. cerevisiae Sep1, for normal mitotic growth and viability.

Current genetics - 1 Sept 1996

Szankasi P, Smith G R

Abstract excerpt

Exonuclease II (ExoII) from Schizosaccharomyces pombe is a 5'-->3' single-stranded DNA exonuclease. We have cloned its gene, exo2, whose nucleotide sequence revealed that ExoII is a homologue of the multifunctional Saccharomyces cerevisiae Sep1 protein (also called Kem1, Xrn1, Rar5, Dst2). S. pombe exo2 null mutants were cold-sensitive for growth, had increased cell size at the restrictive temperature, were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Cell Division

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cloning, Molecular

Share to Fungal Proteins

Share to Molecular Sequence Data

Share to Mutation

Share to Saccharomyces cerevisiae

Source

Identifiers

PMID: 8781170
DOI: 10.1007/s002940050134

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Requirement of S. pombe exonuclease II, a homologue of S. cerevisiae Sep1, for normal mitotic growth and viability.PMID 8781170Read ↗

Identification of functional domains in the Sep1 protein (= Kem1, Xrn1), which is required for transition through meiotic prophase in Saccharomyces cerevisiae.Semantic proximity Read ↗

A role for exonuclease I from S. pombe in mutation avoidance and mismatch correction.Semantic proximity Read ↗

EXO1-A multi-tasking eukaryotic nuclease.Semantic proximity Read ↗

Identification and characterization of <i>Saccharomyces cerevisiae EXO1</i> , a gene encoding an exonuclease that interacts with MSH2Semantic proximity Read ↗

Characterization of nuclease-dependent functions of Exo1p in Saccharomyces cerevisiae.Semantic proximity Read ↗

Complementary functions of the Saccharomyces cerevisiae Rad2 family nucleases in Okazaki fragment maturation, mutation avoidance, and chromosome stability.Semantic proximity Read ↗

Mutational analysis of exoribonuclease I from Saccharomyces cerevisiae.Semantic proximity Read ↗

Synthetic lethality of sep1 (xrn1) ski2 and sep1 (xrn1) ski3 mutants of Saccharomyces cerevisiae is independent of killer virus and suggests a general role for these genes in translation control.Semantic proximity Read ↗

Human Exonuclease 1 (EXO1) Regulatory Functions in DNA Replication with Putative Roles in CancerSemantic proximity Read ↗

Exo1 roles for repair of DNA double-strand breaks and meiotic crossing over in Saccharomyces cerevisiae.Semantic proximity Read ↗

Active-site mutations in the Xrn1p exoribonuclease of Saccharomyces cerevisiae reveal a specific role in meiosis.Semantic proximity Read ↗

Exonuclease 1 and its versatile roles in DNA repair.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.