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Article

Solution structure of all parallel G-quadruplex formed by the oncogene RET promoter sequence.

Nucleic acids research - 1 Aug 2011

Tong Xiaotian, Lan Wenxian, Zhang Xu, Wu Houming, Liu Maili, Cao Chunyang

Abstract excerpt

RET protein functions as a receptor-type tyrosine kinase and has been found to be aberrantly expressed in a wide range of human diseases. A highly GC-rich region upstream of the promoter plays an important role in the transcriptional regulation of RET. Here, we report the NMR solution structure of the major intramolecular G-quadruplex formed on the G-rich strand of this region in K(+) solution. The overall...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21540209
DOI: 10.1093/nar/gkr233
PMCID: PMC3159441

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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