Article
G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells.
Proceedings of the National Academy of Sciences of the United States of America - 1 Jan 1990
Mumby S M, Heukeroth R O, Gordon J I, Gilman A G
Abstract excerpt
Myristoylation of seven different alpha subunits of guanine nucleotide-binding regulatory proteins (G proteins) was examined by expressing these proteins in monkey kidney COS cells. Metabolic labeling studies of cells transfected with cytomegalovirus-based expression vectors indicated that [3H]myristate was incorporated into alpha i1, alpha i2, alpha i3, alpha 0, alpha t, and alpha z but not alpha s subunits. The...
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