Article
Targeting of a G alpha subunit (Gi1 alpha) and c-Src tyrosine kinase to caveolae membranes: clarifying the role of N-myristoylation.
Cellular and molecular biology (Noisy-le-Grand, France) - 1 May 1997
Song K S, Sargiacomo M, Galbiati F, Parenti M, Lisanti M P
Abstract excerpt
Many signaling molecules contain the consensus protein sequence Met-Gly at their N-termini that specifies N-myristoylation. Additionally, some of these proteins contain a cysteine at position-3 (Met-Gly-Cys) that can undergo palmitoylation. As many acylated proteins [G-protein subunits (alpha and...
Topics
- Acylation
- Amino Acid Sequence
- Animals
- COS Cells
- CSK Tyrosine-Protein Kinase
- Caveolin 1
- Caveolins
- Cell Fractionation
- Cell Membrane
- Consensus Sequence
- GTP-Binding Proteins
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Myristic Acids
- Palmitic Acids
- Protein Conformation
- Protein-Tyrosine Kinases