Article
Myristoylation is required for the intracellular localization and endocytic function of ARF6.
Experimental cell research - 1 Nov 1995
D'Souza-Schorey C, Stahl P D
Abstract excerpt
ADP-ribosylation factors (ARFs) are modified by a myristate group that is covalently linked to the second glycine residue at the amino terminus. With the recent evidence that ARF6 localizes to the cell periphery and plays a regulatory role in endocytic traffic, we have investigated the role of myristoylation on the membrane association, biological activity, and subcellular distribution of ARF6 in intact cells. A...
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