Myristoylation is required for the intracellular localization and endocytic function of ARF6.

doi:10.1006/excr.1995.1362

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Article

Myristoylation is required for the intracellular localization and endocytic function of ARF6.

Experimental cell research - 1 Nov 1995

D'Souza-Schorey C, Stahl P D

Abstract excerpt

ADP-ribosylation factors (ARFs) are modified by a myristate group that is covalently linked to the second glycine residue at the amino terminus. With the recent evidence that ARF6 localizes to the cell periphery and plays a regulatory role in endocytic traffic, we have investigated the role of myristoylation on the membrane association, biological activity, and subcellular distribution of ARF6 in intact cells. A...

Topics

ADP-Ribosylation Factors
Animals
Base Sequence
Biological Transport
CHO Cells
Carrier Proteins
Cell Fractionation
Cricetinae
Cytosol
Endocytosis
Fluorescent Antibody Technique

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

GTP-Binding Proteins

Gene Expression

Membrane Proteins

Mevalonic Acid

Molecular Sequence Data

Mutation

Myristates

Source

Open in PubMed

Identifiers

PMID: 7589240
DOI: 10.1006/excr.1995.1362

Genes

ARF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7589240-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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