Article
Glucocorticoid receptor polymorphism is associated with lithium response in bipolar patients.
Neuro endocrinology letters - 1 Jan 2011
Szczepankiewicz Aleksandra, Rybakowski Janusz K, Suwalska Aleksandra, Hauser Joanna
Abstract excerpt
OBJECTIVES: Glucocorticoid receptor has been considered in the pathogenesis of bipolar disorder as it is an important regulator of the circadian rhythm and HPA negative feedback. As glucocorticoid receptor may be possibly related to lithium action we aimed to investigate variation in the GR gene in association with response to lithium treatment in Polish population of bipolar patients. METHODS: We analyzed 115...
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