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Article

Seasonality Patterns in Bipolar Disorder: Associations With Clinical Phenotypes and Treatment-Related Outcomes.

Acta psychiatrica Scandinavica - 1 Apr 2026

Bostan Siralp, Melhuish Beaupre Lindsay M, Ercis Mete, Coombes Brandon J, Romo-Nava Francisco, Prieto Miguel L, Cuellar Barboza Alfredo B, McElroy Susan L, Frye Mark A, Biernacka Joanna M, Ozerdem Aysegul

Abstract excerpt

BACKGROUND: Mood episodes in bipolar disorder (BD) follow a seasonal pattern in approximately 25% of patients. We aimed to examine the associations of specific seasonality patterns in BD with various clinical phenotypes and treatment-related outcomes. METHODS: Patients from the Mayo Clinic Bipolar Disorder Biobank with available seasonality data were included in the study. Among those reporting any seasonality,...

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PMID: 41450248
DOI: 10.1111/acps.70063

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