[Genetic risk factors of neural tube defects].

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

[Genetic risk factors of neural tube defects].

Medycyna wieku rozwojowego - 1 Jan 2000

Sliwerska Elzbieta, Szpecht-Potocka Agnieszka

Abstract excerpt

Neural tube defects (NTDs) are a group of diseases caused by a failure of closure of the neural tube. Its aetiology contains both environmental and genetic factors. NTDs have a polygenic background. Genes, which are linked with NTDs occurrence, are both directly and indirectly connected with controlling the process of closure of the neural tube. Ones of those are genes of metabolism of folic acid as MTHFR, MTR,...

Topics

5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Carrier Proteins
Cystathionine beta-Synthase
Ferredoxin-NADP Reductase
Folic Acid
Genetic Predisposition to Disease
Humans
Methylenetetrahydrofolate Dehydrogenase (NADP)
Methylenetetrahydrofolate Reductase (NADPH2)
Neural Tube Defects
Oxidoreductases Acting on CH-NH Group Donors
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 12810987

Genes

BRCA1
CBS
MTHFR
MTR
MTRR
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics