Article
ATM, BCL2, and TGFβ Gene Polymorphisms as Radiotherapy Outcome Biomarkers in Head and Neck Squamous Cell Carcinoma Patients.
Genetic testing and molecular biomarkers - 1 Dec 2017
Agostini Lidiane P, Stur Elaine, Garcia Fernanda M, Ventorim Diego P, Dos Reis Raquel S, Dettogni Raquel S, Dos Santos Eldamária V W, Peterle Gabriela T, Maia Lucas L, Mendes Suzanny O, de Carvalho Marcos B, Tajara Eloiza H, de Paula Flavia, Dos Santos Marcelo, da Silva Adriana M A, Louro Iúri Drumond
Abstract excerpt
AIMS: Polymorphisms in cell cycle genes are considered prognostic as radiosensitivity markers in patients with head and neck squamous cell carcinoma. Therefore, we aimed to investigate the relationship of ATM 5557G>A, ATM IVS62 + 60G>A, TP53 215G>C, BCL2-938C>A, TGFβ-509C>T, and TGFβ 29C>T with radiotherapy response. MATERIALS AND METHODS: Genotyping was performed by polymerase chain reaction followed by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.