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Article

Impact of site-specific N-glycosylation on cellular secretion, activity and specific activity of the plasma phospholipid transfer protein.

Biochimica et biophysica acta - 1 Jul 2011

Albers John J, Day Joseph R, Wolfbauer Gertrud, Kennedy Hal, Vuletic Simona, Cheung Marian C

Abstract excerpt

The plasma phospholipid transfer protein (PLTP) plays a key role in lipid and lipoprotein metabolism. It has six potential N-glycosylation sites. To study the impact of these sites on PLTP secretion and activity, six variants containing serine to alanine point mutations were prepared by site-directed mutagenesis and expressed in Chinese hamster ovary Flp-In cells. The apparent size of each of the six PLTP mutants...

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Identifiers

PMID: 21515415
DOI: 10.1016/j.bbapap.2011.04.004
PMCID: PMC3112057

Genes

PLTP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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