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Article

Role of glycosylation in transport and enzymic activity of neutral endopeptidase-24.11.

The Biochemical journal - 1 Sept 1994

Lafrance M H, Vézina C, Wang Q, Boileau G, Crine P, Lemay G

Abstract excerpt

Neutral endopeptidase (NEP, EC 3.4.24.11) is a major ectoenzyme of the brush-border membrane. The ectodomain of NEP contains five putative N-glycosylation sites. In order to determine the role of the addition of sugar moieties on the activity and intracellular transport of NEP, we have used site-directed mutagenesis to remove all or some of the five potential sites of sugar addition in membrane-bound and secreted...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 8092997
DOI: 10.1042/bj3020451
PMCID: PMC1137249

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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