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Article

N-glycosylation controls functional activity of Oatp1, an organic anion transporter.

American journal of physiology. Gastrointestinal and liver physiology - 1 Aug 2003

Lee Thomas K, Koh Albert S, Cui Zhifeng, Pierce Robert H, Ballatori Nazzareno

Abstract excerpt

Rat Oatp1 (Slc21a1) is an organic anion-transporting polypeptide believed to be an anion exchanger. To characterize its mechanism of transport, Oatp1 was expressed in Saccharomyces cerevisiae under control of the GAL1 promoter. Protein was present at high levels in isolated S. cerevisiae secretory vesicles but had minimal posttranslational modifications and failed to exhibit taurocholate transport activity....

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Identifiers

PMID: 12702494
DOI: 10.1152/ajpgi.00358.2002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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