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Article

In vivo and in vitro repertoire of CD3+CD4-CD8- thymocytes.

International immunology - 1 Jan 1990

Papiernik M, Pontoux C

Abstract excerpt

CD4-CD8- thymocytes contain a cell subset which expresses the complete CD3-TCR complex (alpha/beta or gamma/delta) of which the ontogeny and filiation are unknown. One of the questions is whether this population can be intrathymically selected, an obligatory step for the mature CD4+ and CD8+ cell differentiation pathway, or if the absence of CD4 an CD8 allows them to escape thymic selection. The repertoire of...

Topics

Animals
Antigens, Differentiation, T-Lymphocyte
CD3 Complex
CD4 Antigens
CD8 Antigens
In Vitro Techniques
Mice
Mice, Inbred Strains
Phenotype
Receptors, Antigen, T-Cell
Receptors, Antigen, T-Cell, alpha-beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Species Specificity

T-Lymphocyte Subsets

Source

Identifiers

PMID: 2150756
DOI: 10.1093/intimm/2.5.407

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2150756-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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