Article
In vivo and in vitro repertoire of CD3+CD4-CD8- thymocytes.
International immunology - 1 Jan 1990
Papiernik M, Pontoux C
Abstract excerpt
CD4-CD8- thymocytes contain a cell subset which expresses the complete CD3-TCR complex (alpha/beta or gamma/delta) of which the ontogeny and filiation are unknown. One of the questions is whether this population can be intrathymically selected, an obligatory step for the mature CD4+ and CD8+ cell differentiation pathway, or if the absence of CD4 an CD8 allows them to escape thymic selection. The repertoire of...
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