Article
Interleukin 7 induces preferential expansion of V beta 8.2+CD4-8- and V beta 8.2+CD4+8- murine thymocytes positively selected by class I molecules.
The Journal of experimental medicine - 1 Aug 1994
Vicari A, de Moraes M do C, Gombert J M, Dy M, Penit C, Papiernik M, Herbelin A
Abstract excerpt
We analyzed the phenotype and V beta-T cell receptor (TCR) repertoire, together with interleukin 7 receptor (IL-7R) expression in unfractionated thymocytes stimulated in vitro with IL-7. This culture system results in a specific proliferation of mature thymocytes belonging to the CD3+CD4-, CD4+8-...
Topics
- Animals
- CD4 Antigens
- CD8 Antigens
- Cells, Cultured
- Histocompatibility Antigens Class I
- Histocompatibility Antigens Class II
- Interleukin-7
- Lymphocyte Activation
- Male
- Mice
- Mice, Inbred C3H