Article
A novel population of T-cell receptor alpha beta-bearing thymocytes which predominantly expresses a single V beta gene family.
Nature - 1 Jan 2000
Fowlkes B J, Kruisbeek A M, Ton-That H, Weston M A, Coligan J E, Schwartz R H, Pardoll D M
Abstract excerpt
Recent studies have demonstrated that CD3 is expressed on a subset of thymocytes with a CD4-CD8- (double negative) phenotype. At least some of these cells bear the CD3-associated gamma delta T-cell receptor (TCR gamma delta). Here we describe a second subset of double negative thymocytes which ex...
Topics
- Animals
- Antigens, Differentiation, T-Lymphocyte
- Antigens, Surface
- Genes
- Immunosorbent Techniques
- Interleukin-1
- Lymphocyte Activation
- Macromolecular Substances
- Mice
- Mice, Inbred BALB C
- Phenotype
- Rats
- Receptors, Antigen, T-Cell
- T-Lymphocytes
- Thymus Gland