Article
Differentiation potential of subsets of CD4-8- thymocytes.
Nature - 1 Jan 2000
Crispe I N, Moore M W, Husmann L A, Smith L, Bevan M J, Shimonkevitz R P
Abstract excerpt
Precursor T cells in the thymus are contained within a subpopulation of thymocytes that lack the markers CD4 and CD8. We have examined the heterogeneity of these cells by flow cytometric analysis, and defined four subpopulations using the cell surface markers Thy-1, J11d and the IL-2 receptor (IL-2R). The J11d+ subset of CD4-8- cells all bear the antigen Thy-1, and some express the IL-2R. Staining and RNA...
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