Article
T cell receptor V beta repertoire in mice lacking endogenous mouse mammary tumor provirus.
European journal of immunology - 1 Mar 1995
Braun M Y, Jouvin-Marche E, Marche P N, MacDonald H R, Acha-Orbea H
Abstract excerpt
When endogenous mouse mammary tumor virus (MMTV) superantigens (SAg) are expressed in the first weeks of life an efficient thymic deletion of T cells expressing MMTV SAg-reactive T cell receptor (TcR) V beta segments is observed. As most inbred mouse strains and wild mice contain integrated MMTV DNA, knowing the precise extent of MMTV influence on T cell development is required in order to study T cell...
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