Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional dissection of Polycomb repressive complex 1 reveals the importance of a charged domain.

Cold Spring Harbor symposia on quantitative biology - 1 Jan 2010

Grau D J, Antao J M, Kingston R E

Abstract excerpt

Silencing of homeotic genes requires the Polycomb repressive complex 1 (PRC1) family of protein complexes, which are composed of Polycomb-group (PcG) proteins and frequently include other subunits. We discuss here two aspects of PRC1 that might contribute to this activity. Inhibiting the action of remodeling factors via chromatin compaction is believed to be one mechanism by which PRC1 represses genes. We show...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin
Share to Conserved Sequence
Share to Drosophila melanogaster

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to HeLa Cells

Share to Polycomb-Group Proteins

Share to Repressor Proteins

Share to Structure-Activity Relationship

Source

Identifiers

PMID: 21502414
DOI: 10.1101/sqb.2010.75.056

Genes

PRC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional dissection of Polycomb repressive complex 1 reveals the importance of a charged domain.PMID 21502414Read ↗

Compaction of chromatin by diverse Polycomb group proteins requires localized regions of high charge.Semantic proximity Read ↗

Mutation of a nucleosome compaction region disrupts Polycomb-mediated axial patterning.Semantic proximity Read ↗

Drosophila chromosome condensation proteins Topoisomerase II and Barren colocalize with Polycomb and maintain Fab-7 PRE silencing.Semantic proximity Read ↗

The genetic basis for PRC1 complex diversity emerged early in animal evolution.Semantic proximity Read ↗

A Polycomb domain found in committed cells impairs differentiation when introduced into PRC1 in pluripotent cells.Semantic proximity Read ↗

Enhancer of Polycomb is a suppressor of position-effect variegation in Drosophila melanogaster.Semantic proximity Read ↗

CHMP1 is a novel nuclear matrix protein affecting chromatin structure and cell-cycle progression.Semantic proximity Read ↗

Dynamic regulation by polycomb group protein complexes controls pattern formation and the cell cycle in Drosophila.Semantic proximity Read ↗

The polyhomeotic gene of Drosophila encodes a chromatin protein that shares polytene chromosome-binding sites with Polycomb.Semantic proximity Read ↗

Histone acetylation and the maintenance of chromatin compaction by Polycomb repressive complexes.Semantic proximity Read ↗

Polycomb group targeting through different binding partners of RING1B C-terminal domain.Semantic proximity Read ↗

The Drosophila Enhancer of zeste gene encodes a chromosomal protein: examination of wild-type and mutant protein distribution.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.