Article
The genetic basis for PRC1 complex diversity emerged early in animal evolution.
Proceedings of the National Academy of Sciences of the United States of America - 15 Sept 2020
Gahan James M, Rentzsch Fabian, Schnitzler Christine E
Abstract excerpt
Polycomb group proteins are essential regulators of developmental processes across animals. Despite their importance, studies on Polycomb are often restricted to classical model systems and, as such, little is known about the evolution of these important chromatin regulators. Here we focus on Polycomb Repressive Complex 1 (PRC1) and trace the evolution of core components of canonical and non-canonical PRC1...
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