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Article

The Drosophila Enhancer of zeste gene encodes a chromosomal protein: examination of wild-type and mutant protein distribution.

Development (Cambridge, England) - 1 Dec 1996

Carrington E A, Jones R S

Abstract excerpt

The Drosophila Enhancer of zeste [E(z)] gene is a member of the Polycomb-group and, as such, is involved in maintaining the transcriptional repression of the homeotic genes of the Antennapedia (ANT-C) and bithorax (BX-C) complexes. It has been proposed that Polycomb-group (Pc-G)-mediated silencing requires the formation of heteromeric protein complexes which modify the chromatin structure of target genes. We...

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Identifiers

PMID: 9012527
DOI: 10.1242/dev.122.12.4073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The Drosophila Enhancer of zeste gene encodes a chromosomal protein: examination of wild-type and mutant protein distribution.PMID 9012527Read ↗

E(z): a polycomb group gene or a trithorax group gene?Semantic proximity Read ↗

Genetic analysis of the enhancer of zeste locus and its role in gene regulation in Drosophila melanogaster.Semantic proximity Read ↗

The Trithorax-mimic allele of Enhancer of zeste renders active domains of target genes accessible to polycomb-group-dependent silencing in Drosophila melanogaster.Semantic proximity Read ↗

In vivo analysis of Drosophila SU(Z)12 function.Semantic proximity Read ↗

The Drosophila Polycomb-group gene Enhancer of zeste contains a region with sequence similarity to trithorax.Semantic proximity Read ↗

Drosophila enhancer of Zeste/ESC complexes have a histone H3 methyltransferase activity that marks chromosomal Polycomb sites.Semantic proximity Read ↗

The polyhomeotic gene of Drosophila encodes a chromatin protein that shares polytene chromosome-binding sites with Polycomb.Semantic proximity Read ↗

Mapping functional domains of the polycomb protein of Drosophila melanogaster.Semantic proximity Read ↗

A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression.Semantic proximity Read ↗

zeste, a nonessential gene, potently activates Ultrabithorax transcription in the Drosophila embryo.Semantic proximity Read ↗

The Drosophila trithorax gene encodes a chromosomal protein and directly regulates the region-specific homeotic gene fork head.Semantic proximity Read ↗

Mutations in polycombeotic, a Drosophila polycomb-group gene, cause a wide range of maternal and zygotic phenotypes.Semantic proximity Read ↗

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