Article
The enhancer of trithorax and polycomb gene Caf1/p55 is essential for cell survival and patterning in Drosophila development.
Development (Cambridge, England) - 1 May 2011
Anderson Aimée E, Karandikar Umesh C, Pepple Kathryn L, Chen Zhihong, Bergmann Andreas, Mardon Graeme
Abstract excerpt
In vitro data suggest that the human RbAp46 and RbAp48 genes encode proteins involved in multiple chromatin remodeling complexes and are likely to play important roles in development and tumor suppression. However, to date, our understanding of the role of RbAp46/RbAp48 and its homologs in metazoan development and disease has been hampered by a lack of insect and mammalian mutant models, as well as redundancy due...
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