Article
SNR1 is an essential subunit in a subset of Drosophila brm complexes, targeting specific functions during development.
Developmental biology - 15 Jan 2003
Zraly Claudia B, Marenda Daniel R, Nanchal Runjhun, Cavalli Giacomo, Muchardt Christian, Dingwall Andrew K
Abstract excerpt
The snr1 gene of Drosophila melanogaster encodes a conserved component of the multiprotein Brahma (Brm) complex, a counterpart to the SWI/SNF complexes that participate in ATP-dependent chromatin remodeling. Loss-of-function and null mutations in the snr1 gene reveal its essential role in Drosophila development. We identified new mutant alleles and ectopically expressed deleted forms to dissect the specific...
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