Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The biological function of the WD40 repeat-containing protein p55/Caf1 in Drosophila.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Mar 2012

Wen Pei, Quan Zhenghui, Xi Rongwen

Abstract excerpt

BACKGROUND: The p55 family WD40 repeat-containing histone chaperone proteins are components of several chromatin regulatory complexes (such as PRC2, NURF and CAF-1) and interact with histone H4, yet their functional relevance in vivo is unclear. RESULTS: Here we use Drosophila as a genetic model to dissect the function of p55/Caf1 during development. In agree with a recent report, we find that p55 is essential...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Proliferation
Share to Cell Survival

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila melanogaster

Share to Drosophila Proteins

Share to Gene Expression Regulation, Developmental

Share to Gene Silencing

Share to Histone-Lysine N-Methyltransferase

Share to Histones

Source

Identifiers

PMID: 22241697
DOI: 10.1002/dvdy.23730

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The biological function of the WD40 repeat-containing protein p55/Caf1 in Drosophila.PMID 22241697Read ↗

The enhancer of trithorax and polycomb gene Caf1/p55 is essential for cell survival and patterning in Drosophila development.Semantic proximity Read ↗

Structural basis of histone H4 recognition by p55.Semantic proximity Read ↗

Alternative splicing of NURF301 generates distinct NURF chromatin remodeling complexes with altered modified histone binding specificities.Semantic proximity Read ↗

The components of Drosophila histone chaperone dCAF-1 are required for the cell death phenotype associated with rbf1 mutation.Semantic proximity Read ↗

Developmental roles of the Mi-2/NURD-associated protein p66 in Drosophila.Semantic proximity Read ↗

The Polycomb Group Protein Pcgf1 Is Dispensable in Zebrafish but Involved in Early Growth and Aging.Semantic proximity Read ↗

Asf1 is required for viability and chromatin assembly during DNA replication in vertebrate cells.Semantic proximity Read ↗

The Drosophila DAXX-Like Protein (DLP) Cooperates with ASF1 for H3.3 Deposition and Heterochromatin Formation.Semantic proximity Read ↗

TAF250 is required for multiple developmental events in Drosophila.Semantic proximity Read ↗

Ubiquitin-activating/conjugating activity of TAFII250, a mediator of activation of gene expression in Drosophila.Semantic proximity Read ↗

The complexity of PRC2 catalysts CLF and SWN in plants.Semantic proximity Read ↗

The tumor suppressor PRDM5 regulates Wnt signaling at early stages of zebrafish development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.