Article
A role for tuned levels of nucleosome remodeler subunit ACF1 during Drosophila oogenesis.
Developmental biology - 15 Mar 2016
Börner Kenneth, Jain Dhawal, Vazquez-Pianzola Paula, Vengadasalam Sandra, Steffen Natascha, Fyodorov Dmitry V, Tomancak Pavel, Konev Alexander, Suter Beat, Becker Peter B
Abstract excerpt
The Chromatin Accessibility Complex (CHRAC) consists of the ATPase ISWI, the large ACF1 subunit and a pair of small histone-like proteins, CHRAC-14/16. CHRAC is a prototypical nucleosome sliding factor that mobilizes nucleosomes to improve the regularity and integrity of the chromatin fiber. This may facilitate the formation of repressive chromatin. Expression of the signature subunit ACF1 is restricted during...
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