Article
Correcting away the hidden heritability.
Annals of human genetics - 1 May 2011
Williams Scott M, Haines Jonathan L
Abstract excerpt
In the age of high-density genome-wide association (GWAS) data, correcting for multiple comparisons is a substantial issue for genetic epidemiological studies. However, the current manuscript review process generally requires both stringent correction and independent replication. The result of this stringency is that studies that are published suffer from inflated Type 2 error rates (false negatives), thereby...
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