Article
Explaining additional genetic variation in complex traits.
Trends in genetics : TIG - 1 Apr 2014
Robinson Matthew R, Wray Naomi R, Visscher Peter M
Abstract excerpt
Genome-wide association studies (GWAS) have provided valuable insights into the genetic basis of complex traits, discovering >6000 variants associated with >500 quantitative traits and common complex diseases in humans. The associations identified so far represent only a fraction of those that influence phenotype, because there are likely to be many variants across the entire frequency spectrum, each of which...
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