Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Elements of 'missing heritability'.

Current opinion in cardiology - 1 May 2012

Marian Ali J

Abstract excerpt

PURPOSE OF REVIEW: To discuss the basis of 'missing heritability', which has emerged as an enigma in the post-genome-wide association studies (GWAS) era. RECENT FINDINGS: Alleles identified through GWAS account for a relatively small fraction of heritability of the complex phenotypes. Accordingly, a significant part of heritability of the complex traits remains unaccounted for ('missing heritability'). Recent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Epigenomics
Share to Gene-Environment Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Predisposition to Disease

Share to Genetic Variation

Share to Genome-Wide Association Study

Share to Phenotype

Source

Identifiers

PMID: 22450721
DOI: 10.1097/HCO.0b013e328352707d

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Elements of 'missing heritability'.PMID 22450721Read ↗

Missing heritability and strategies for finding the underlying causes of complex disease.Semantic proximity Read ↗

Finding the missing heritability of complex diseases.Semantic proximity Read ↗

Inferring the nature of missing heritability in human traitsSemantic proximity Read ↗

The mystery of missing heritability: Genetic interactions create phantom heritability.Semantic proximity Read ↗

Heritability in the genome-wide association era.Semantic proximity Read ↗

Missing heritability: is the gap closing? An analysis of 32 complex traits in the Lifelines Cohort Study.Semantic proximity Read ↗

Epigenetic inheritance and the missing heritabilitySemantic proximity Read ↗

Twins and the mystery of missing heritability: the contribution of gene-environment interactions.Semantic proximity Read ↗

Disease genetics: insights into missing heritability.Semantic proximity Read ↗

The 'missing heritability' of common disorders: should health researchers care?Semantic proximity Read ↗

Missing heritability of complex diseases: Enlightenment by genetic variants from intermediate phenotypes.Semantic proximity Read ↗

Quantitative genetics: heritability is not always missing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.