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Article

Subcellular localization and role of lipin-1 in human macrophages.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 2011

Valdearcos Martín, Esquinas Esperanza, Meana Clara, Gil-de-Gómez Luis, Guijas Carlos, Balsinde Jesús, Balboa María A

Abstract excerpt

The lipins have been described as metabolic enzymes that regulate lipid biosynthesis and also signaling processes by controlling the cellular concentration of bioactive lipids, phosphatidic acid, and diacylgycerol. In the present work we have studied the subcellular localization and role of lipin-1 in human monocyte-derived macrophages. Human macrophages express lipin-1 isoforms α and β. A transfected...

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Identifiers

PMID: 21478406
DOI: 10.4049/jimmunol.1003279

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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