Article
Lipins: multifunctional lipid metabolism proteins.
Annual review of nutrition - 21 Aug 2010
Csaki Lauren S, Reue Karen
Abstract excerpt
The lipin proteins are evolutionarily conserved proteins with roles in lipid metabolism and disease. There are three lipin protein family members in mammals and one or two orthologs in plants, invertebrates, and single-celled eukaryotes. Studies in yeast and mouse led to the identification of two distinct molecular functions of lipin proteins. Lipin proteins have phosphatidate phosphatase activity and catalyze...
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