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Article

Overexpression of perilipin1 protects against atheroma progression in apolipoprotein E knockout mice.

Atherosclerosis - 1 Feb 2018

Yamamoto Kohei, Miyoshi Hideaki, Cho Kyu Yong, Nakamura Akinobu, Greenberg Andrew S, Atsumi Tatsuya

Abstract excerpt

BACKGROUND AND AIMS: Perilipin1 (PLIN1), a lipid droplet-associated protein, plays an important role in the regulation of lipolysis and lipid storage in adipocytes. PLIN1 has recently been reported to be expressed in macrophages within atheroma plaques, suggesting PLIN1 may play a role in the accumulation of lipids at the arterial wall and in the development of atherosclerosis. To clarify the role of PLIN1 in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29407594
DOI: 10.1016/j.atherosclerosis.2018.01.019

Genes

PLIN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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