Article
Concordance between two phenotypic assays and ultradeep pyrosequencing for determining HIV-1 tropism.
Antimicrobial agents and chemotherapy - 1 Jun 2011
Saliou Adrien, Delobel Pierre, Dubois Martine, Nicot Florence, Raymond Stéphanie, Calvez Vincent, Masquelier Bernard, Izopet Jacques
Abstract excerpt
There have been few studies on the concordance between phenotypic assays for predicting human immunodeficiency virus type 1 (HIV-1) coreceptor usage. The sensitivity of ultradeep pyrosequencing combined with genotyping tools is similar to that of phenotypic assays for detecting minor CXCR4-using variants. We evaluated the agreement between two phenotypic assays, the Toulouse tropism test (TTT) and the Trofile...
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