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Article

Characterization of CXCR4-using HIV-1 during primary infection by ultra-deep pyrosequencing.

The Journal of antimicrobial chemotherapy - 1 Dec 2013

Raymond Stéphanie, Saliou Adrien, Nicot Florence, Delobel Pierre, Dubois Martine, Carcenac Romain, Sauné Karine, Marchou Bruno, Massip Patrice, Izopet Jacques

Abstract excerpt

OBJECTIVES: R5 viruses have long been thought to account for almost all strains present in primary HIV-1 infections (PHIs), but recent studies using sensitive phenotypic assays have revealed that 3%-6.4% of subjects also harbour CXCR4-using viruses. Phenotypic assays provide only qualitative results: the presence or absence of CXCR4-using viruses. We have therefore used ultra-deep pyrosequencing (UDS) to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23869053
DOI: 10.1093/jac/dkt290

Genes

CXCR4
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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