Article
Performance of genotypic algorithms for predicting HIV-1 tropism measured against the enhanced-sensitivity Trofile coreceptor tropism assay.
Journal of clinical microbiology - 1 Nov 2010
Sánchez Victoria, Masiá Mar, Robledano Catalina, Padilla Sergio, Ramos José Manuel, Gutiérrez Félix
Abstract excerpt
The objectives of this study were to assess the performance of genotypic algorithms for predicting CXCR4-using virus, with enhanced sensitivity Trofile HIV coreceptor tropism assay (ES Trofile) as the reference, and to compare the concordance/accuracy of genotypic tests with ES Trofile and with the original Trofile assay. Paired phenotypic and genotypic determinations of HIV-1 coreceptor usage were compared in...
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