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Article

Flying-patch patch-clamp study of G22E-MscL mutant under high hydrostatic pressure.

Biophysical journal - 6 Apr 2011

Petrov Evgeny, Rohde Paul R, Martinac Boris

Abstract excerpt

High hydrostatic pressure (HHP) present in natural environments impacts on cell membrane biophysical properties and protein quaternary structure. We have investigated the effect of high hydrostatic pressure on G22E-MscL, a spontaneously opening mutant of Escherichia coli MscL, the bacterial mechanosensitive channel of large conductance. Patch-clamp technique combined with a flying-patch device and hydraulic setup...

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Identifiers

PMID: 21463576
DOI: 10.1016/j.bpj.2011.02.016
PMCID: PMC3072613

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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