Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HIV Quasispecies Dynamics during Pro-Active Treatment Switching: Impact on Multi-Drug Resistance and Resistance Archiving in Latent Reservoirs

24 Mar 2011

Abstract excerpt

The human immunodeficiency virus (HIV) can be suppressed by highly active anti-retroviral therapy (HAART) in the majority of infected patients. Nevertheless, treatment interruptions inevitably result in viral rebounds from persistent, latently infected cells, necessitating lifelong treatment. Virological failure due to resistance development is a frequent event and the major threat to treatment success....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS drug development and treatment
Share to HIV/AIDS Research and Interventions
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21455303
DOI: 10.1371/journal.pone.0018204

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIV Quasispecies Dynamics during Pro-Active Treatment Switching: Impact on Multi-Drug Resistance and Resistance Archiving in Latent ReservoirsPMID 21455303Read ↗

Optimal Antiviral Switching to Minimize Resistance Risk in HIV TherapySemantic proximity Read ↗

Understanding patterns of HIV multi-drug resistance through models of temporal and spatial drug heterogeneity.Semantic proximity Read ↗

Understanding patterns of HIV multi-drug resistance through models of temporal and spatial drug heterogeneitySemantic proximity Read ↗

Dynamics of drug resistance-associated mutations in HIV-1 DNA reverse transcriptase sequence during effective ART.Semantic proximity Read ↗

Comparison of different treatment regimens for the emergence of new resistance under therapy.Semantic proximity Read ↗

Characterizing early drug resistance-related events using geometric ensembles from HIV protease dynamicsSemantic proximity Read ↗

Mutation takes no vacation: can structured treatment interruptions increase the risk of drug-resistant HIV-1?Semantic proximity Read ↗

Mathematical approaches in the study of viral kinetics and drug resistance in HIV-1 infection.Semantic proximity Read ↗

Antiretroviral dynamics determines HIV evolution and predicts therapy outcome.Semantic proximity Read ↗

Longitudinal Detection and Persistence of Minority Drug-Resistant Populations and Their Effect on Salvage Therapy.Semantic proximity Read ↗

Evolution of drug-resistant viral populations during interruption of antiretroviral therapy.Semantic proximity Read ↗

Characterizing drug resistance using geometric ensembles from HIV protease dynamicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.