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Characterizing early drug resistance-related events using geometric ensembles from HIV protease dynamics

12 Dec 2018

Abstract excerpt

The use of antiretrovirals (ARVs) has drastically improved the life quality and expectancy of HIV patients since their introduction in health care. Several millions are still afflicted worldwide by HIV and ARV resistance is a constant concern for both healthcare practitioners and patients, as while treatment options are finite, the virus constantly adapts via complex mutation patterns to select for resistant...

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PMID: 30560871
DOI: 10.1038/s41598-018-36041-8

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