Article
Potential role of anti-oncogenes in aging.
Mechanisms of ageing and development - 30 Apr 1990
Ferluga J
Abstract excerpt
Some observations on cellular senescence are discussed regarding the possibility that the postulated genes, which bring about the DNA synthesis block of senescent fibroblasts, might be similar to those designated as anti-oncogenes or tumour suppressor genes. The latter genes have been defined by tumorogenicity tests of hybrids from fused tumour and normal cells, of which the retinoblastoma (RB) gene is a...
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