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Article

KRAS, BRAF and PIK3CA mutations in human colorectal cancer: relationship with metastatic colorectal cancer.

Oncology reports - 1 Jun 2011

Li Hong-Tao, Lu Yuan-Yuan, An Yan-Xin, Wang Xin, Zhao Qing-Chuan

Abstract excerpt

Many abnormal gene expressions and dysregulated signaling pathways have been found in human colorectal cancer. Activating mutations of the KRAS, BRAF or PIK3CA oncogenes are frequently found in colorectal cancer. The aim of the study was to investigate the molecular occurrence of KRAS, BRAF and PIK3CA mutations in the colorectal tumorigenesis and to study the association of these events with clinicopathological...

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Identifiers

PMID: 21424126
DOI: 10.3892/or.2011.1217

Genes

KRAS
BRAF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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