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Article

A Systematic Review and Meta-analysis on the Occurrence of Biomarker Mutation in Colorectal Cancer among the Asian Population.

BioMed research international - 1 Jan 2022

Afolabi Hafeez, Md Salleh Salzihan, Zakaria Zaidi, Seng Ch'ng Ewe, Mohd Nafil Siti Norasikin Binti, Abdul Aziz Ahmad Aizat Bin, Wada Yusuf, Irekeola Ahmad

Abstract excerpt

Globally, colorectal carcinoma (CRC) is the third most common cancer and the third major cause of cancer-related death in both sexes. KRAS and BRAF mutations are almost mutually exclusively involved in the pathogenesis of CRC. Both are major culprits in treatment failure and poor prognosis for CRC. Method. A systematic review and meta-analysis of various research was done following the Preferred Reporting Items...

Topics

Biomarkers
Codon
Colorectal Neoplasms
Female
Humans
Male
Mutation
Pakistan
Proto-Oncogene Proteins B-raf
Proto-Oncogene Proteins p21(ras)

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35782059
DOI: 10.1155/2022/5824183
PMCID: PMC9246611

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-35782059-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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