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Article

Exploring the Relationship Between KRAS, NRAS, and BRAF Mutations and Clinical Characteristics in Iranian Colorectal Cancer Patients.

Journal of gastrointestinal cancer - 1 Sept 2024

Mosaferi Zahra, Pirestani Majid, Arefian Ehsan, Gojani Goli, Kavousinasab Nastaran, Karimi Parto, Deilami Azam, Abrehdari-Tafreshi Zahra

Abstract excerpt

BACKGROUND: Patients with colorectal cancer can benefit from anti-EGFR (epidermal growth factor receptor) therapy. However, this therapy is not effective for treating colorectal cancers with constitutive activating mutations in the KRAS, NRAS, and BRAF genes. Molecular analysis of tumor tissue frequently informs treatment decisions for colorectal cancer. This study aims to identify KRAS, NRAS, and BRAF mutations...

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Identifiers

PMID: 38709419
DOI: 10.1007/s12029-024-01064-0

Genes

KRAS
NRAS
BRAF
EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Exploring the Relationship Between KRAS, NRAS, and BRAF Mutations and Clinical Characteristics in Iranian Colorectal Cancer Patients.PMID 38709419Read ↗

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