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Article

Mutation patterns and prognostic analysis of BRAF/KRAS/PIK3CA in colorectal cancer.

Journal of clinical laboratory analysis - 1 Jun 2022

Wang Chengfeng, Pan Diling

Abstract excerpt

BACKGROUND AND OBJECTIVE: Aberrant gene expression and abnormal signaling pathways often occur in patients with colorectal cancer, in which mutations in B-Raf Proto-Oncogene (BRAF), KRAS Proto-Oncogene (KRAS), and Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha (PIK3CA) are quite common. In this study, the relationship between BRAF, KRAS, and PIK3CA mutations and clinicopathologic features...

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Identifiers

PMID: 35435290
DOI: 10.1002/jcla.24444
PMCID: PMC9169172

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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