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Article

Mutations of KRAS and PIK3CA as independent predictors of distant metastases in colorectal cancer.

Medical oncology (Northwood, London, England) - 1 Jul 2014

Zhu Kunli, Yan Hongjiang, Wang Renben, Zhu Hui, Meng Xiangjiao, Xu Xiaoqing, Dou Xue, Chen Dong

Abstract excerpt

The objective was to evaluate DNA mutations of KRAS, BRAF, and PIK3CA and their clinicopathological correlations with colorectal cancer (CRC) and to identify their contribution to distant metastases in CRC. A total of 148 tumor samples were obtained from patients with CRC in the Shandong Tumor Hospital and Institute between January 2008 and December 2009. DNA was extracted for polymerase chain reaction...

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Source

Identifiers

PMID: 24861917
DOI: 10.1007/s12032-014-0016-6

Genes

KRAS
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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