Article
Mutation Analysis of KRAS and BRAF Genes in Metastatic Colorectal Cancer: a First Large Scale Study from Iran.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2016
Koochak Aghigh, Rakhshani Nasser, Karbalaie Niya Mohammad Hadi, Tameshkel Fahimeh Safarnezhad, Sohrabi Masoud Reza, Babaee Mohammad Reza, Rezvani Hamid, Bahar Babak, Imanzade Farid, Zamani Farhad, Khonsari Mohammad Reza, Ajdarkosh Hossein, Hemmasi Gholamreza
Abstract excerpt
BACKGROUND: The investigation of mutation patterns in oncogenes potentially can make available a reliable mechanism for management and treatment decisions for patients with colorectal cancer (CRC). This study concerns the rate of KRAS and BRAF genes mutations in Iranian metastatic colorectal cancer (mCRC) patients, as well as associations of genotypes with clinicopathological features. MATERIALS AND METHODS: A...
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