Article
IMPACT OF KRAS MUTATIONS IN CLINICAL FEATURES IN COLORECTAL CANCER.
Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery - 1 Jan 2020
Zanatto Renato Morato, Santos Gianni, Oliveira Júnea Caris, Pracucho Eduardo Marcucci, Nunes Adauto José Ferreira, Lopes-Filho Gaspar Jesus, Saad Sarhan Sydney
Abstract excerpt
BACKGROUND: KRAS mutations are important events in colorectal carcinogenesis, as well as negative predictors of response to EGFR inhibitors treatment. AIM: To investigate the association of clinical-pathological features with KRAS mutations in colorectal cancer patients treated. METHODS: Data from 69 patients with colorectal cancer either metastatic at diagnosis or later, were retrospectively analyzed. The direct...
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