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Article

Variants of GCKR affect both β-cell and kidney function in patients with newly diagnosed type 2 diabetes: the Verona newly diagnosed type 2 diabetes study 2.

Diabetes care - 1 May 2011

Bonetti Sara, Trombetta Maddalena, Boselli Maria Linda, Turrini Fabiola, Malerba Giovanni, Trabetti Elisabetta, Pignatti Pier Franco, Bonora Enzo, Bonadonna Riccardo C

Abstract excerpt

OBJECTIVE: In genome-wide association studies, performed mostly in nondiabetic individuals, genetic variability of glucokinase regulatory protein (GCKR) affects type 2 diabetes-related phenotypes, kidney function, and risk of chronic kidney disease (CKD). We tested whether GCKR variability affects type 2 diabetes or kidney-related phenotypes in newly diagnosed type 2 diabetes. RESEARCH DESIGN AND METHODS: In 509...

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Identifiers

PMID: 21411509
DOI: 10.2337/dc10-2218
PMCID: PMC3114499

Genes

GCKR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Variants of GCKR affect both β-cell and kidney function in patients with newly diagnosed type 2 diabetes: the Verona newly diagnosed type 2 diabetes study 2.PMID 21411509Read ↗

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