Article
The GCKR Gene Polymorphism rs780094 is a Risk Factor for Gestational Diabetes in a Brazilian Population.
Journal of clinical laboratory analysis - 1 Mar 2017
Anghebem-Oliveira Mauren Isfer, Webber Susan, Alberton Dayane, de Souza Emanuel Maltempi, Klassen Giseli, Picheth Geraldo, Rego Fabiane Gomes de Moraes
Abstract excerpt
BACKGROUND: The glucokinase regulatory protein (GCKR) regulates the activity of the glucokinase (GCK), which plays a key role in glucose homeostasis. Genetic variants in GCK have been associated with diabetes and gestational diabetes (GDM). Due to the relationship between GCKRP and GCK, polymorphisms in GCKR are also candidates for genetic association with GDM. The aim of this study was to evaluate the...
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