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Article

Genetic variability of GCKR alters lipid profiles in children with monogenic and autoimmune diabetes.

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Oct 2014

Tracz A, Madzio J, Gnys P, Malachowska B, Borowiec M, Wyka K, Jarosz-Chobot P, Mysliwiec M, Szadkowska A, Mlynarski W, Fendler W

Abstract excerpt

PURPOSE: Mutations in the glucokinase (GCK) gene are associated with altered blood glucose and lipid concentrations. Our aim was to assess the effects on HbA1c and serum lipid levels of single nucleotide polymorphisms (SNPs) in 2 genes encoding proteins that interact with glucokinase: glucose-6-phospatase catalytic subunit 2 (G6PC2) and glucokinase regulatory protein (GCKR). METHODS: The study group included 129...

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Share to Adaptor Proteins, Signal Transducing
Share to Cholesterol, LDL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

Share to Glucose-6-Phosphatase

Share to Glycated Hemoglobin

Share to Homozygote

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Source

Identifiers

PMID: 24918535
DOI: 10.1055/s-0034-1375648

Genes

GCK
GCKR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Genetic variability of GCKR alters lipid profiles in children with monogenic and autoimmune diabetes.PMID 24918535Read ↗

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