Contribution of Type 2 Diabetes Susceptible Gene GCKR Polymorphisms Rs780094 and Rs1260326 to Gestational Diabetes Mellitus: A Meta-Analysis

doi:10.2174/0118715303313654241101042033

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Contribution of Type 2 Diabetes Susceptible Gene GCKR Polymorphisms Rs780094 and Rs1260326 to Gestational Diabetes Mellitus: A Meta-Analysis

Endocrine, metabolic & immune disorders drug targets - 1 Jan 2026

Zhang Yuke, Wang Kuangyi, Ji Chenxi, Lin Yansi, Liu Zitong, Chen Jing, Zheng Feifei, Yang Xiaoqin, Sun Yi

Abstract excerpt

BACKGROUND: There is still no conclusive understanding of whether the glucokinase regulator (GCKR) gene rs780094 and rs1260326 polymorphisms predispose to gestational diabetes mellitus (GDM). OBJECTIVE: This systematic review and meta-analysis aimed to determine the effect of the GCKR polymorphisms on GDM susceptibility. METHODS: Seven literature databases were searched (from inception to February 17, 2024) to...

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Topics

Humans

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Female

Diabetes, Gestational

Genetic Predisposition to Disease

Pregnancy

Polymorphism, Single Nucleotide

Diabetes Mellitus, Type 2

Adaptor Proteins, Signal Transducing

Genetic Association Studies

Source

Open in PubMed Open full text

Identifiers

PMID: 39806965
DOI: 10.2174/0118715303313654241101042033
PMCID: PMC13284661

Genes

GCKR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 18 Oct 2026.

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